System Requirements

VariantMiner is a web-based application that runs in modern web browsers. Since the heavy computational work is done on the server, your local system requirements are minimal.

Browser Requirements

Supported Browsers

VariantMiner works best with modern web browsers that support:

  • HTML5

  • CSS Grid and Flexbox

  • ES6 JavaScript

  • WebSockets for real-time updates

Recommended Browsers:

  • Chrome 90+ (Recommended)

  • Firefox 88+

  • Safari 14+

  • Microsoft Edge 90+

Browser Settings

Ensure the following browser features are enabled:

  • JavaScript: Required for interactive features

  • Cookies: Required for authentication

  • Local Storage: Used for user preferences

  • Pop-ups: May be needed for file downloads

Network Requirements

Internet Connection

  • Minimum: Stable broadband connection (10 Mbps)

  • Recommended: High-speed connection (50+ Mbps) for large file uploads

  • Upload Speed: Important for VCF file uploads (files can be several GB)

Firewall Considerations

Ensure access to:

  • HTTPS traffic on port 443

  • WebSocket connections for real-time updates

  • File upload/download capabilities

Hardware Requirements

Minimum System Specifications

  • RAM: 4 GB

  • Processor: Dual-core processor

  • Storage: Minimal local storage required

  • Display: 1024x768 resolution

  • RAM: 8 GB or more

  • Processor: Quad-core processor

  • Storage: SSD for better browser performance

  • Display: 1920x1080 or higher resolution

File Size Limitations

VCF Files

  • Maximum file size: Varies by deployment (typically 10-50 GB)

  • Compressed files: .gz compression is supported and recommended

  • Processing time: Larger files take longer to process

BAM Files

  • Maximum file size: Varies by deployment

  • Index files: .bai index files should be uploaded alongside BAM files

Performance Considerations

Large Dataset Handling

  • VCF files with millions of variants are supported

  • Processing time scales with file size and variant count

  • Progress indicators show processing status

Concurrent Users

The platform supports multiple concurrent users with:

  • Isolated workspaces for data security

  • Shared resources for common operations

  • Real-time collaboration features

Mobile Device Support

Tablets

  • iPad: Safari 14+ supported

  • Android tablets: Chrome 90+ supported

  • Screen size: 10" or larger recommended

Smartphones

  • Limited functionality on small screens

  • View-only access for monitoring

  • Full features require tablet or desktop

Accessibility

VariantMiner strives to be accessible:

  • Keyboard navigation support

  • Screen reader compatibility

  • High contrast color options

  • Configurable font sizes

Common Issues and Solutions

Slow File Uploads

  • Check internet upload speed

  • Use .gz compressed VCF files

  • Upload during off-peak hours

  • Consider splitting very large files

Browser Performance

  • Close unnecessary browser tabs

  • Clear browser cache regularly

  • Disable unnecessary browser extensions

  • Use Chrome for best performance

Display Issues

  • Ensure browser zoom is set to 100%

  • Update to latest browser version

  • Check for JavaScript errors in console

  • Try incognito/private browsing mode

Getting Help

If you experience technical issues:

  1. Check your browser console for error messages

  2. Try a different browser

  3. Contact your system administrator


System ready? Continue to Logging In to access VariantMiner.

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